shinyBioTools

A standalone R Shiny application for biological data analysis.

Features

• Real-time PCR Analysis: Analyze qPCR data using the delta-delta-CT method with visualization
• shRNA Primer Design: Design shRNA primers using splashRNA database queries
• Drug Synergy Analysis: Calculate drug synergy scores using ZIP, HSA, Bliss, and Loewe models

Quick Start

Simply run the R script directly:

# In RStudio or R console
source("R/app.R")

Or from terminal:

Rscript R/app.R

The application will open at http://localhost:5001

Requirements

• R >= 4.5.0
• R packages: shiny, shinydashboard, tidyverse, magrittr, patchwork, writexl, readxl, stringr, Biostrings, httr, xml2, limma, tibble, synergyfinder

Install packages:

BiocManager::install(c(
  "shiny", "shinydashboard", "tidyverse", "magrittr", "patchwork", "writexl",
  "readxl", "stringr", "Biostrings", "httr", "xml2", "limma", "tibble", "synergyfinder"
))

Author

Hao He haohe90@gmail.com

License

MIT License