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phase-variation

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sachdevalab / MODIFI

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MODIFI is for detecting DNA base modifications and linking ECEs to their microbial hosts using PacBio metagenomic data. It performs modification calling, motif discovery, and host–ECE association analysis, supporting both HiFi and subread data.

motif metagenomics borg dna-methylation ece plasmid phage mge epigenomics dna-modification pacbio-sequencing pacbio-hifi-sequencing-reads mge-host-linkage meta-epigenomics phase-variation ece-host-linkage
  • Updated Apr 1, 2026
  • Python

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